Microfluidics
Contract development of biological microfluidic analytical systems
Capabilities
We design and fabricate microfluidic cartridges in polymers (PC, PMMA, COP/COC). We have the equipment and experience to implement various methods of microchip fabrication and processing, including injection molding, heat pressing, milling and laser ablation.
We design and develop microfluidic systems based on various types of pumps, as well as Lab-on-a-chip and Organ-on-a-chip systems.
We design and manufacture analytical instruments with microfluidic cartridges for molecular diagnostics (PCR-analyzers, immunoanalyzers, fluorescent microchip scanners).
We provide selection and testing of materials for microfluidic cartridges, their biocompatibility and optical properties.
Sealed cartridges
Nucleic acid amplifiers developed by Trobio use PCR cartridges made with different types of sealing.
The number of reaction chambers of a PCR cartridge reaction chambers can vary from one to six.
The method of PCR cartridge sealing varies depending on the design of the amplifier, with various specialized films, silicone beads, or specialized plastic.
The number of reaction chambers of a PCR cartridge reaction chambers can vary from one to six.
The method of PCR cartridge sealing varies depending on the design of the amplifier, with various specialized films, silicone beads, or specialized plastic.
Each method is highly efficient (over 99%), allowing the cartridges to be used not only for PCR analysis, but also for other experiments that require guaranteed sealing of the reaction chamber.
Plastic injection molding technology is used for the mass production of PCR cartridges in a thermoplastic injection molding machine (TPM). This method has a number of advantages, namely low cost, quality and reliability, as well as simplified scalability for large batch production.
Plastic injection molding technology is used for the mass production of PCR cartridges in a thermoplastic injection molding machine (TPM). This method has a number of advantages, namely low cost, quality and reliability, as well as simplified scalability for large batch production.
Organ-on-Chip
Organs-on-Chip (OOC) are microfluidic systems designed to grow cellular structures under various conditions. The key idea of using OOC is to simulate the operation of individual organs or groups of organs under laboratory conditions. Depending on the experimental conditions, it is possible to change physical, chemical, or biological parameters of the cultivation.
Organs-on-Chip technology applications
Pharmacology and toxicology
Organs-on-Chip technology is used to improve the development of new drugs and individualize the drug therapy, making it possible to avoid experiments on animals.
Organs-on-Chip technology is used to improve the development of new drugs and individualize the drug therapy, making it possible to avoid experiments on animals.
Basic research
Studies of cellular response and the interrelationship of different cell cultures
Studies of cellular response and the interrelationship of different cell cultures
Personalized medicine
Using patient's primary cells for treatment optimization.
Using patient's primary cells for treatment optimization.
Lab-on-a-chip
Current bioanalytical applications require a compact and simple solution. Laboratory-on-Chip (LOC) allows combining functionally different laboratory devices, serial processing of initial sample up to final result, increasing speed of samples processing, excluding "human factor" from the process.
Submit a request for developing a biological microfluidic analytical system